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These CHI Profiles provides a state-level assessment of healthcare capacity, population vulnerability, and infrastructure resilience to support pediatric disaster preparedness and response. Each profile integrates data on healthcare access, manufacturing and distribution networks, socioeconomic conditions, and natural hazard risks to identify key strengths and gaps within the healthcare ecosystem. By combining these insights, the CHI Profiles help inform planning, strengthen supply chain continuity, and guide targeted investments that enhance the safety and well-being of children and families before, during, and after emergencies.